Palmoplantar keratosis (PPK) is a skin condition characterized by thickening of the skin on the palms and soles. It occurs due to excessive production of keratin, a protein that protects the skin. PPK can be hereditary or develop later in life due to various causes.

Symptoms

• Thickened, hard skin on the palms and/or soles
• Dry, scaly, or cracked skin
• Callus formation, sometimes with painful fissures
• Sensitivity or pain when walking or gripping
• In some cases, redness and inflammation around the thickened skin

Cause

Genetic factors: Some forms of PPK are inherited and run in families.
Acquired causes: PPK can develop due to prolonged pressure or friction, such as excessive walking, using tools, or wearing poorly fitting shoes.
Skin conditions: Psoriasis and eczema can lead to excessive callus formation on the palms and soles.
Systemic diseases: Certain metabolic or autoimmune diseases can cause PPK.
Infections: Fungal or bacterial infections may contribute to skin thickening.

Diagnosis

• The doctor diagnoses PPK based on the visible characteristics of the skin.
• A skin biopsy may be performed to rule out other conditions.
• Blood tests can be conducted if an underlying disease is suspected.

Treatment

Moisturizing creams: Use of urea or salicylic acid creams to soften the thickened skin.
Callus removal: A doctor or podiatrist can remove excess callus to relieve pain and discomfort.
Medication: In severe cases, retinoids may be prescribed to regulate skin growth.
Treatment of underlying conditions: If PPK is caused by an illness or infection, treating that condition is necessary.

Self-care tips

Moisturize daily with a rich cream or lotion containing urea or lactic acid.
Avoid prolonged pressure and friction by wearing comfortable shoes and gloves.
Use mild soaps to prevent skin dryness.
Soak hands and feet regularly in warm water with bath oil to keep the skin soft.
Avoid extreme temperatures as heat and cold can worsen symptoms.

PPK is a chronic condition that may not completely disappear, but with proper care, symptoms can be significantly reduced.

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